| 10/22/2021 | University of Science and Arts (Okla.) |  | Shawnee | W 107-75 | 
                            
                                
                                    
                                        | 11/2/2021 | Arlington Baptist University |  | SHAWNEE | W 98-49 | 
                            
                                
                                    
                                        | 11/12/2021 | Wayne State College |  | SHAWNEE | W 74-61 | 
                            
                                
                                    
                                        | 11/13/2021 | Minnesota State University Moorhead |  | SHAWNEE | W 90-87 (2 OT) | 
                            
                                
                                    
                                        | 11/19/2021 | at Missouri Western State University |  | St. Joseph, MO | L 71-74 | 
                            
                                
                                    
                                        | 11/23/2021 | at Washburn University |  | Topeka, KS | W 69-63 | 
                            
                                
                                    
                                        | 11/26/2021 | at West Texas A&M University |  | Canyon, TX | L 58-61 | 
                            
                                
                                    
                                        | 11/27/2021 | vs. Eastern New Mexico |  | Canyon, TX | L 66-70 | 
                            
                                
                                    
                                        | 12/2/2021 | at Northwestern Oklahoma State | * | Alva, OK | W 64-60 | 
                            
                                
                                    
                                        | 12/4/2021 | at Southwestern Oklahoma State | * | Weatherford, OK | W 79-67 | 
                            
                                
                                    
                                        | 12/11/2021 | Southeastern Oklahoma State | * | Shawnee, Okla. | L 64-82 | 
                            
                                
                                    
                                        | 12/18/2021 | East Central | * | Shawnee, OK | W 82-71 | 
                            
                                
                                    
                                        | 12/30/2021 | at Henderson State | * | Arkadelphia, AR | W 83-78 | 
                            
                                
                                    
                                        | 1/1/2022 | at Ouachita Baptist | * | Arkadelphia, Ark. | Postponed | 
                            
                                
                                    
                                        | 1/6/2022 | Harding | * | Shawnee, OK | W 83-62 | 
                            
                                
                                    
                                        | 1/8/2022 | Arkansas Tech | * | Shawnee, OK | Postponed | 
                            
                                
                                    
                                        | 1/11/2022 | at Ouachita Baptist | * | Arkadelphia, AR | W 77-71 | 
                            
                                
                                    
                                        | 1/13/2022 | at Southern Nazarene | * | Bethany, OK | L 73-93 | 
                            
                                
                                    
                                        | 1/15/2022 | Northwestern Oklahoma State | * | Shawnee, OK | W 82-75 | 
                            
                                
                                    
                                        | 1/20/2022 | at Southern Arkansas | * | Magnolia, AR | Postponed | 
                            
                                
                                    
                                        | 1/22/2022 | at Arkansas-Monticello | * | Monticello, AR | W 80-68 | 
                            
                                
                                    
                                        | 1/24/2022 | at Southern Arkansas | * | Magnolia, AR | L 63-71 | 
                            
                                
                                    
                                        | 1/27/2022 | Ouachita Baptist | * | Shawnee, OK | W 60-57 | 
                            
                                
                                    
                                        | 1/29/2022 | Henderson State | * | Shawnee, OK | W 90-81 | 
                            
                                
                                    
                                        | 2/3/2022 | Southern Nazarene | * | SHAWNEE | Postponed | 
                            
                                
                                    
                                        | 2/5/2022 | Southwestern Oklahoma State | * | Shawnee, OK | W 67-62 | 
                            
                                
                                    
                                        | 2/7/2022 | Arkansas Tech | * | Shawnee, OK | W 80-73 | 
                            
                                
                                    
                                        | 2/10/2022 | at Arkansas Tech | * | Russellville, AR | W 76-70 | 
                            
                                
                                    
                                        | 2/12/2022 | at Harding | * | Searcy, AR | L 66-69 | 
                            
                                
                                    
                                        | 2/14/2022 | Southern Nazarene | * | Shawnee, OK | W 73-65 | 
                            
                                
                                    
                                        | 2/17/2022 | Arkansas-Monticello | * | Shawnee, OK | W 63-62 | 
                            
                                
                                    
                                        | 2/19/2022 | Southern Arkansas | * | Shawnee, OK | W 76-72 | 
                            
                                
                                    
                                        | 2/25/2022 | at Southeastern Oklahoma State | * | Durant, OK | L 76-80 | 
                            
                                
                                    
                                        | 2/26/2022 | at East Central | * | Ada, OK | W 76-58 | 
                            
                                
                                    
                                        | 3/3/2022 | vs. Southwestern Oklahoma State |  | Shawnee, OK | L 56-68 |