| 11/1/2021 | at UT-Arlington (EXH) |  | Arlington, Texas | L 64-68 | 
                            
                                
                                    
                                        | 11/12/2021 | vs. Minnesota State University Moorhead |  | Shawnee, OK | L 78-79 | 
                            
                                
                                    
                                        | 11/13/2021 | vs. Wayne State College |  | Shawnee, OK | W 80-64 | 
                            
                                
                                    
                                        | 11/17/2021 | Arlington Baptist |  | Durant, Okla. | W 128-70 | 
                            
                                
                                    
                                        | 11/23/2021 | at Drury University |  | Springfield, MO | W 90-61 | 
                            
                                
                                    
                                        | 11/24/2021 | vs. Missouri S&T |  | Springfield, MO | W 104-102 | 
                            
                                
                                    
                                        | 12/2/2021 | at Southwestern Oklahoma State | * | Weatherford, OK | W 77-76 | 
                            
                                
                                    
                                        | 12/4/2021 | Southern Nazarene | * | Durant, OK | W 82-71 | 
                            
                                
                                    
                                        | 12/11/2021 | at Oklahoma Baptist | * | Shawnee, Okla. | W 82-64 | 
                            
                                
                                    
                                        | 12/15/2021 | Seattle Pacific |  | Durant, OK | W 81-69 | 
                            
                                
                                    
                                        | 12/18/2021 | at Northwestern Oklahoma State | * | Alva, OK | W 72-58 | 
                            
                                
                                    
                                        | 12/30/2021 | at Arkansas Tech | * | Russellville, AR | Postponed | 
                            
                                
                                    
                                        | 1/1/2022 | at Harding | * | Searcy, AR | L 73-76 | 
                            
                                
                                    
                                        | 1/6/2022 | Arkansas-Monticello | * | Durant, OK | W 85-58 | 
                            
                                
                                    
                                        | 1/8/2022 | Southern Arkansas | * | Durant, OK | W 103-73 | 
                            
                                
                                    
                                        | 1/13/2022 | East Central | * | Durant, OK | L 113-115 2 OT | 
                            
                                
                                    
                                        | 1/15/2022 | Southwestern Oklahoma State | * | Durant, Okla. | Postponed | 
                            
                                
                                    
                                        | 1/20/2022 | at Ouachita Baptist | * | Arkadelphia, AR | W 81-65 | 
                            
                                
                                    
                                        | 1/22/2022 | at Henderson State | * | Arkadelphia, AR | L 73-84 | 
                            
                                
                                    
                                        | 1/27/2022 | Harding | * | Durant, OK | W 115-58 | 
                            
                                
                                    
                                        | 1/29/2022 | Arkansas Tech | * | Durant, OK | W 74-67 | 
                            
                                
                                    
                                        | 2/3/2022 | at East Central | * | Ada, Okla. | Postponed | 
                            
                                
                                    
                                        | 2/5/2022 | at Southern Nazarene | * | Bethany, OK | W 94-93 OT | 
                            
                                
                                    
                                        | 2/7/2022 | Southwestern Oklahoma State | * | Durant, OK | W 87-78 | 
                            
                                
                                    
                                        | 2/10/2022 | at Southern Arkansas | * | Magnolia, AR | L 62-77 | 
                            
                                
                                    
                                        | 2/12/2022 | at Arkansas-Monticello | * | Monticello, AR | W 78-69 | 
                            
                                
                                    
                                        | 2/17/2022 | Henderson State | * | Durant, OK | W 85-80 | 
                            
                                
                                    
                                        | 2/19/2022 | Ouachita Baptist | * | Durant, OK | W 72-56 | 
                            
                                
                                    
                                        | 2/20/2022 | at East Central | * | Ada, OK | W 84-74 | 
                            
                                
                                    
                                        | 2/22/2022 | at Arkansas Tech | * | Russellville, AR | W 75-68 | 
                            
                                
                                    
                                        | 2/25/2022 | Oklahoma Baptist | * | Durant, OK | W 80-76 | 
                            
                                
                                    
                                        | 2/26/2022 | Northwestern Oklahoma State | * | Durant, OK | W 91-60 | 
                            
                                
                                    
                                        | 3/3/2022 | vs. East Central |  | Shawnee, OK | W 82-59 | 
                            
                                
                                    
                                        | 3/5/2022 | vs. Southern Nazarene |  | Shawnee, OK | L 74-77 |